Intelligent Design, Biodiversity and Antiobesity
Today I want to be focused in other aspects of my studies based on an Intelligent Design inference.
Like in other events of genetic variation, the simplest equation to describe obesity is:
Susceptible Genes + Predisposing Environment = Obesity
Here, as we saw yesterday, the conceptual model is likening the genes to the inner biological software (IBS
) possessor of an inherent Intelligent Design, activated and modulated by the environment. The environment can be compared to one of the upper levels of computational assembly, the biological hardware.
If the genetic morphologies or mutations that trigger obesity are present, then obesity will develop, favored by a predisposing environment which activates its expression; however, such environment can be deliberately controlled (i.e.
, by diets and exercise) either to counteract or to inhibit the negative effects of those altered genes.
Methodologies similar to microarrays, both for transcripts and for proteins, will be helpful to better describe the identities and functions of genes and genomes. Being both of them components of the biological program, which is the precise, complex and natural genetic software contributor to the expression of health, as well as to the pathological reprogramming of life when altered.
The discovery of genes expressed only in particular tissues (tissue-specific
) will also be helpful in our understanding of the precise design to fulfill specific purposes by the proteins. Each cell being compared to a factory, and working all the tissues as synchronized machines under an intense molecular communication, to the end that the full body may also be able to fulfill its own and purposeful design.
Here, methodologies similar to the microarrays can also help us to differentiate the expression of genes among different organisms, unraveling not only specific genes within families and tissues, but also species-specific
genes, proteins and metabolic processes.
Specific cells under altered environments can start producing genes not supposed to be present there, unfolding the process of disease. If those strange genes or alterations can be detected at the very moment of its pathological triggering, then we will be able to prevent its out-of-control expression. Environmental mutations are generally altering the normal gene expression, causing collateral effects rather than improvement, starting thus a pathological state for the organism.
Allelomorphs are the agents of a wide array of polymorphisms, many of them with only aesthetic variations, independent of any environmental pressure. The field of healthy allelomorphs
remains still an "unexplored land", even when more than 135 years have already passed since the publication of the original work of Mendel related to the Laws of Heredity
By following Intelligent Design methodologies, I have proposed that we can be able to generate biodiversity, excluding molecular methodologies and using only those well-known "Laws of Heredity
" of Mendel. Even until today, we are still lacking of the proper identification of biological varieties in nature
By the other hand, molecular studies based on Intelligent Design principles will have the purpose to discover non-invasive and reversible treatments; for example, against human obesity, targeting exclusively the fat cells. This is a deliberate "reprogramming of life", specifically directed to correct genetic anomalies, i.e., by temporarily "turning-off" the expression of a protein, i.e., perilipin, which is the molecule involved in fat storage within our adipose tissues.